Useful info
Unlike a virus, bacteria are full-fledged living microorganisms, many of which successfully coexist with humans. For example, it is the microflora in the intestines that helps us efficiently absorb food.
Scientists distinguish three groups of bacteria:
1. Pathogenic - those that always lead to disease. These are salmonella, pale treponema, and gonococcus.
2. Conditionally pathogenic - microbes that live on mucous membranes, skin, in the environment and under normal conditions are not dangerous to health. But with reduced immunity or other factors, they can lead to diseases. This group includes, in particular, streptococcus, E. coli, staphylococcus aureus.
3. Non-pathogenic - harmless, sometimes beneficial to the human body.
The danger of diseases caused by bacteria is that some of these microorganisms are capable of releasing strong poisons in the process of life - exotoxins that cause severe intoxication and damage to organs and tissues (diphtheria, tetanus, botulism) .
The most common bacterial diseases:
Each of us encounters bacterial diseases more than once in our lives. Bacteria are the most common cause of pneumonia, a complication of viral infections. They also cause sore throats (streptococci) and inflammation of the middle ear (pneumococci). Bacteria are the causative agents of such infections:
DIPHTHERIA is an acute infectious disease caused by Corynebacterium diphteriae (diphtheria bacillus), characterized by fibrinous (diphtheritic or croupous) inflammation in the area of the entrance gate and general intoxication. Pathogenic properties of diphtheria bacillus are associated mainly with the release of exotoxin.
• Clinical and morphological forms: diphtheria of the pharynx (oropharynx, tonsils) and diphtheria of the respiratory tract (larynx, trachea, bronchi - croupous fibrinous inflammation, the cause of true croup with rejection of films), other rare forms by localization (diphtheria of wounds, etc.).
• Heart damage - early paralysis (toxic cardiomyopathy at the end of the 1st - beginning of the 2nd week of illness),late paralysis (after 2-2.5 months from the onset of the disease as a result of damage to the vagus nerve and intramural ganglia).
SCARLET FEVER is an acute infectious disease with a predominant lesion of the pharynx (catarrhal inflammation with severe hyperemia - “flaming throat”, follicular, lacunar, necrotic tonsillitis) and exanthema, caused by group A β-hemolytic streptococcus. The same streptococci also cause other infections (tonsillitis, streptoderma and etc.). Possible scarlet fever with other entrance gates ("extrabuccal"). Primary scarlet fever complex: lymphangitis and regional lymphadenitis.
• Forms of severe scarlet fever: toxic, septic.
• Late complications ("second period" of scarlet fever): myocarditis, glomerulonephritis.
MENINGOCOCCAL DISEASE is an acute infectious disease caused by the Gram-positive diplococcus Neisseria meningitidis.
• Forms of meningococcal infection: localized - meningococcal carriage, acute nasopharyngitis (catarrhal inflammation); generalized - meningococcemia (meningococcal sepsis, the main manifestations are endotoxin shock with DIC), meningitis, meningoencephalitis (purulent inflammation), mixed forms. Meningococcemia is characterized by bilateral massive hemorrhage in the adrenal glands with the development of acute adrenal insufficiency (Waterhouse-Friderichsen syndrome). This syndrome can also occur in other severe infectious diseases in children and debilitated patients.
INTESTINAL INFECTIONS. There are diseases accompanied by bacteremia (typhoid fever, salmonellosis), and "local" infections, the pathogens of which do not go beyond the intestines (shigellosis/dysentery, cholera, amoebiasis).
BACTERIAL DYSENTERY (SHIGELLOSIS) is an acute intestinal infection caused by 4 types of shigella and manifested by colitis with diarrhea, tenesmus, abdominal pain, and in case of severe course - bloody diarrhea, fever and severe intoxication.
COLITIS: can be catarrhal, fibrinous (diphtheritic), ulcerative. The outcome is complete healing or scarring. In children, a follicular-ulcerative variant of colitis is isolated.
• Complications: intestinal - perforation of ulcers, peritonitis, intestinal phlegmon, intestinal bleeding, cicatricial stenosis of the intestine; extraintestinal - bronchopneumonia, pyelonephritis, arthritis, pylephlebitic liver abscesses. In chronic course, the development of cachexia and amyloidosis is possible.
TYPHOID FEVER is an acute intestinal infectious disease caused by Salmonella typhi and characterized by a cyclic course with phase change, granulomatous inflammation in the lymphoid apparatus of the intestine (mainly small), intoxication, hepato- and splenomegaly. Local changes develop in the terminal ileum (ileotif), sometimes in the large intestine (colotif), but more often both the small and large intestine (ileocolotyphos) are affected.
• Stages of ileotyphoid (each lasting about 1 week): cerebri-like swelling of grouped lymphoid follicles (Peyer's patches), necrosis, ulceration (dirty ulcer stage), clear ulcers, and healing.
• General changes(due to bacteremia): typhoid exanthema on the skin of the trunk and abdomen, Duguet's tonsillitis (swelling of the tonsils), typhoid granulomas in the spleen, lymph nodes, bone marrow, lungs.
• Complications: intestinal - bleeding, perforation of ulcers, peritonitis; extraintestinal - bronchopneumonia (superinfection, more often caused by pneumococcus and staphylococcus aureus), purulent perichondritis of the larynx, waxy necrosis of the rectus abdominis muscles, purulent osteomyelitis and intramuscular abscesses, sepsis.
SALMONELLOSIS combines up to half of all intestinal infections, affects the small intestine (enteritis), manifestations are associated with endotoxin and endotoxemia.
• Forms of salmonellosis: gastrointestinal and generalized.
• Complications: infectious-toxic shock, acute renal failure.
CHOLERA is a quarantine infection (pathogens - Vibrio cholerae and Vibrio eltor), an acute disease with a primary lesion of the stomach and small intestine, characterized by a general severe condition and dehydration.
• Clinical and morphological stages: cholera enteritis, cholera gastroenteritis, cholera algid with a picture of exsicosis (dehydration).
• Complications: specific - cholera typhoid (diphtheritic colitis due to the addition of a secondary infection), productive intracapillary glomerulonephritis, chlorhydropenic uremia (necrotizing nephrosis with cortical necrosis); nonspecific - accession of a secondary infection, pneumonia, abscesses, phlegmon, sepsis.
SEPSIS is a severe acyclic generalized infectious process characterized by severe systemic manifestations (systemic inflammatory response syndrome - SIRS). More often it is a complication of a severe infection of various localization, less often - an independent nosological form.
• Generalized infections caused by viruses, rickketsia, chlamydia and mycoplasmas, it is not accepted to refer to sepsis. Sepsis caused by gram-positive flora usually proceeds according to the type of septicopyemia, the main morphological criterion for the generalization of infection are metastatic purulent foci. The disease caused by gram-negative flora often proceeds according to the type of bacterial (endotoxin) shock, the main morphological criterion for the generalization of infection is DIC and other signs of shock.
Bacterial diseases are very difficult to tolerate and require treatment under medical supervision. Without medical attention, many of them can be fatal.